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N-methyltyramine

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  • N-methyltyramine

Product Property

Product Status : New
Sample Available : yes
Shipment Terms : Negotiable
Payment Mode : T/T,L/C

Description

methyltyramine

N-methyltyramine

New bodybuilding supplementN-Methyltyramine, NMT
Cas number: 370-98-9
Appreance: White crystalline powder
Assay: 99%

Synonyms: Methyltyramine, N-methyltyramine, 4-hydroxy-N-methylphenethylamine, NMT

What is n-methyltyramine?

N-Methyltyramine is the methylated versionof L-Tyramine (through the addition of a methyl group at the N terminal), anaturally occurring monoamine compound that acts as a catecholamine releasingagent. N-Methyltyramine can be found in nature from plants such as barley andCitrus aurantium, the latter being commonly used for Synephrine content(N-Methyltyramine is converted to Synephrine by Dopamine β -hydroxylase).Unlike Synephrine, N-Methyltyramine has not been observed to display anylipolytic activity, due to the lack of a beta-hydroxyl or a beta-ketone. It’smechanisms of action imply that it acts as a peripheral sympathomimeticcompound. NMT is similar to Synephrine and Hordenine, with the addition of ahydroxyl group at β distinguishing Synephrine from NMT, and substitution of adimethyl group at the N terminal resulting in Hordenine.

In general, when dealing with sympathomimetic compounds, a primary or secondaryaliphatic amine separated by 2 carbons from a substituted benzene ring isminimally required for high agonist activity. Along with possessing thischaracteristic common to adrenergic agents, the presence of a hydroxyl group inthe benzene ring at the 4th position shows that N-Methyltyramine has excellentalpha and beta activity adrenergic receptor activity.

N-Methyltyramine (NMT), also known as 4-hydroxy-N-methylphenethylamine, is a natural phenethylamine alkaloidfound in a variety of plants.As the name implies, it is the N-methyl analog orderivative of the well-known biogenicamine, tyramine, with which it shares many pharmacological properties(see below). Biosynthetically, NMT is produced by the N-methylationof tyramine via the action of the enzyme tyramine N-methyltransferase.

Benefits of taking N-methyltyramine:

1. Significantlyincrease adrenergic, dopaminergic and serotonergic neurotransmitters by

acting asan indirect sympathomimetic amine.

2. Increasesinsulin secretion and decreases blood sugar levels.

3. Increaseplasma and myocardial cGMP and cAMP levels.


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